Ultrasound, liver abnormal after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 21 reports of ultrasound, liver abnormal in dogs after Amoxicillin + Clavulanate. That is 0.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports

9.5%Marked serious

9.5%Recovered

33%Died or euthanised

–Typical onset

How the animals did

Recovered

2 9.5%

Still unwell when reported

2 9.5%

Died

6 29%

Euthanised

1 4.8%

Not known

10 48%

Problems reported at the same time

Liver problems

21 100%

Vomiting

9 43%

Kidney problems

9 43%

Abnormal ultrasound finding

8 38%

8 38%

7 33%

6 29%

6 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause ultrasound, liver abnormal in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with ultrasound, liver abnormal