Pulmonary disorder after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 33 reports of pulmonary disorder in dogs after Amoxicillin + Clavulanate. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

33Reports

79%Marked serious

9.1%Recovered

45%Died or euthanised

32 daysTypical onset

How soon it started

Same day

1 3.4%

1–2 days

3 10%

3–7 days

4 14%

1–4 weeks

6 21%

Over a month

15 52%

How the animals did

Recovered

2 6.1%

Recovered with lasting effects

1 3.0%

Still unwell when reported

12 36%

Died

6 18%

Euthanised

9 27%

Not known

3 9.1%

Problems reported at the same time

Abnormal radiograph finding

23 70%

18 55%

16 48%

15 45%

13 39%

12 36%

11 33%

Didn't work as expected

11 33%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause pulmonary disorder in dogs?: 33 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 32 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pulmonary disorder with similar medicines

Pulmonary disorder after Doxycycline 23 reports · 0.6% of its reports

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with pulmonary disorder