Pale mucous membrane after Amoxicillin + Clavulanate (Clavamox) in dogs

127 reports to the FDA describe pale mucous membrane in dogs given Amoxicillin + Clavulanate. That is 2.4% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

127Reports
64%Marked serious
5.5%Recovered
54%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
13 16%
1–2 days
13 16%
3–7 days
17 20%
1–4 weeks
22 27%
Over a month
18 22%

How the animals did

Recovered
7 5.5%
Still unwell when reported
31 24%
Died
40 31%
Euthanised
28 22%
Not known
21 17%

Problems reported at the same time

Age of the animals

Under 1 year
25
1–3 years
17
4–7 years
23
8–11 years
34
12+ years
25

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause pale mucous membrane in dogs?
127 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pale mucous membrane with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with pale mucous membrane