Blood in stool after Amoxicillin + Clavulanate (Clavamox) in dogs

The FDA has received 75 reports of blood in stool in dogs after Amoxicillin + Clavulanate. That is 1.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

75Reports
33%Marked serious
2.7%Recovered
35%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
3 9.4%
1–2 days
8 25%
3–7 days
4 13%
1–4 weeks
6 19%
Over a month
11 34%

How the animals did

Recovered
2 2.7%
Still unwell when reported
16 21%
Died
18 24%
Euthanised
8 11%
Not known
31 41%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
7
4–7 years
16
8–11 years
25
12+ years
18

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause blood in stool in dogs?
75 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in stool with similar medicines

All reported side effects of Amoxicillin + Clavulanate in dogs · Medicines most reported with blood in stool