Blood in stool after Amoxicillin in dogs

The FDA has received 23 reports of blood in stool in dogs after Amoxicillin. That is 1.7% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

23Reports

57%Marked serious

4.3%Recovered

17%Died or euthanised

3 daysTypical onset

How soon it started

Same day

5 38%

1–2 days

1 7.7%

3–7 days

2 15%

1–4 weeks

2 15%

Over a month

3 23%

How the animals did

Recovered

1 4.3%

Still unwell when reported

6 26%

Died

1 4.3%

Euthanised

3 13%

Not known

12 52%

Problems reported at the same time

17 74%

15 65%

13 57%

11 48%

Abnormal radiograph finding

8 35%

Leucocytosis

8 35%

Lethargy

8 35%

Diarrhea

7 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Amoxicillin treats bacterial infections.

Questions owners ask

Can Amoxicillin cause blood in stool in dogs?: 23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood in stool with similar medicines

Blood in stool after Amoxicillin + Clavulanate (Clavamox) 75 reports · 1.4% of its reports
Blood in stool after Doxycycline 30 reports · 0.7% of its reports
Blood in stool after Cefovecin (Convenia) 38 reports · 1.0% of its reports
Blood in stool after Enrofloxacin (Baytril) 43 reports · 1.1% of its reports
Blood in stool after Metronidazole 79 reports · 2.6% of its reports

All reported side effects of Amoxicillin in dogs · Medicines most reported with blood in stool