Tremors after Praziquantel + Pyrantel in cats

44 reports to the FDA describe tremors in cats given Praziquantel + Pyrantel. That is 3.5% of all reports for this medicine, compared with 2.6% across reports for all cat medicines.

44Reports

45%Marked serious

39%Recovered

6.8%Died or euthanised

Same dayTypical onset

How soon it started

Same day

20 71%

1–2 days

3 11%

3–7 days

2 7.1%

1–4 weeks

0 0.0%

Over a month

3 11%

How the animals did

Recovered

17 39%

Still unwell when reported

2 4.5%

Died

2 4.5%

Euthanised

1 2.3%

Not known

22 50%

Problems reported at the same time

24 55%

12 27%

12 27%

9 20%

7 16%

6 14%

5 11%

Head bobbing

4 9.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause tremors in cats?: 44 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

Tremors after Emodepside + Praziquantel (Profender) 348 reports · 6.1% of its reports
Tremors after Praziquantel 25 reports · 1.5% of its reports
Tremors after Pyrantel 38 reports · 6.8% of its reports

All reported side effects of Praziquantel + Pyrantel in cats · Medicines most reported with tremors