Restlessness or agitation after Lotilaner (Credelio) in cats
The FDA has received 95 reports of restlessness or agitation in cats after Lotilaner. That is 11% of all reports for this medicine, compared with 4.9% across reports for all cat medicines, so it is reported unusually often with this medicine.
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Lotilaner kills fleas and ticks; monthly chewable.
Products with this ingredient include Credelio. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Lotilaner cause restlessness or agitation in cats?
- 95 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Restlessness or agitation with similar medicines
- Restlessness or agitation after Fluralaner (Bravecto) 346 reports · 3.3% of its reports
- Restlessness or agitation after Sarolaner + Selamectin (Revolution Plus) 162 reports · 2.0% of its reports
- Restlessness or agitation after Fluralaner + Moxidectin (Bravecto Plus) 107 reports · 3.3% of its reports
All reported side effects of Lotilaner in cats · Medicines most reported with restlessness or agitation