Fever after Lotilaner (Credelio) in cats
The FDA has received 52 reports of fever in cats after Lotilaner. That is 5.8% of all reports for this medicine, compared with 3.2% across reports for all cat medicines, so it is reported unusually often with this medicine.
52Reports
50%Marked serious
44%Recovered
1.9%Died or euthanised
Same dayTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Lotilaner kills fleas and ticks; monthly chewable.
Products with this ingredient include Credelio. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Lotilaner cause fever in cats?
- 52 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Fever with similar medicines
- Fever after Fluralaner (Bravecto) 194 reports · 1.8% of its reports
- Fever after Sarolaner + Selamectin (Revolution Plus) 182 reports · 2.2% of its reports
- Fever after Fluralaner + Moxidectin (Bravecto Plus) 64 reports · 2.0% of its reports
All reported side effects of Lotilaner in cats · Medicines most reported with fever