Lethargy after Lotilaner (Credelio) in cats
131 reports to the FDA describe lethargy in cats given Lotilaner. That is 15% of all reports for this medicine, compared with 14% across reports for all cat medicines.
131Reports
38%Marked serious
29%Recovered
9.9%Died or euthanised
1 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Lotilaner kills fleas and ticks; monthly chewable.
Products with this ingredient include Credelio. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Lotilaner cause lethargy in cats?
- 131 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 1 day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Lethargy with similar medicines
- Lethargy after Fluralaner (Bravecto) 1,243 reports · 12% of its reports
- Lethargy after Sarolaner + Selamectin (Revolution Plus) 1,018 reports · 12% of its reports
- Lethargy after Fluralaner + Moxidectin (Bravecto Plus) 391 reports · 12% of its reports
- Lethargy after Sarolaner (Simparica) 26 reports · 10% of its reports
All reported side effects of Lotilaner in cats · Medicines most reported with lethargy