Incorrect route of drug administration after Emodepside + Praziquantel (Profender) in cats

74 reports to the FDA describe incorrect route of drug administration in cats given Emodepside + Praziquantel. That is 1.3% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

74Reports
28%Marked serious
34%Recovered
0.0%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
39 95%
1–2 days
1 2.4%
3–7 days
0 0.0%
1–4 weeks
0 0.0%
Over a month
1 2.4%

How the animals did

Recovered
25 34%
Still unwell when reported
4 5.4%
Not known
45 61%

Problems reported at the same time

Age of the animals

Under 1 year
20
1–3 years
17
4–7 years
16
8–11 years
3
12+ years
9

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause incorrect route of drug administration in cats?
74 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with incorrect route of drug administration