Drug dose administration interval too short after Emodepside + Praziquantel (Profender) in cats

37 reports to the FDA describe drug dose administration interval too short in cats given Emodepside + Praziquantel. That is 0.6% of all reports for this medicine, compared with 0.4% across reports for all cat medicines, so it is reported unusually often with this medicine.

37Reports

43%Marked serious

22%Recovered

0.0%Died or euthanised

17 daysTypical onset

How soon it started

Same day

1 3.2%

1–2 days

0 0.0%

3–7 days

4 13%

1–4 weeks

21 68%

Over a month

5 16%

How the animals did

Recovered

8 22%

Not known

29 78%

Problems reported at the same time

35 95%

3 8.1%

3 8.1%

2 5.4%

Drug dose administration interval too long

1 2.7%

Weight gain

1 2.7%

Loss of appetite

1 2.7%

Respiratory tract infection

1 2.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause drug dose administration interval too short in cats?: 37 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 17 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with drug dose administration interval too short