Didn't work as expected after Omeprazole in horses

The FDA has received 1,708 reports of didn't work as expected in horses after Omeprazole. That is 88% of all reports for this medicine, compared with 23% across reports for all horse medicines, so it is reported unusually often with this medicine.

1,708Reports

14%Marked serious

18%Recovered

1.1%Died or euthanised

32 daysTypical onset

How soon it started

Same day

60 4.1%

1–2 days

11 0.8%

3–7 days

17 1.2%

1–4 weeks

534 37%

Over a month

838 57%

How the animals did

Recovered

300 18%

Recovered with lasting effects

2 0.1%

Still unwell when reported

569 33%

Died

1 0.1%

Euthanised

18 1.1%

Not known

818 48%

Problems reported at the same time

93 5.4%

69 4.0%

43 2.5%

25 1.5%

24 1.4%

19 1.1%

18 1.1%

Digestive tract disorder

14 0.8%

Age of the animals

Under 1 year

1–3 years

4–7 years

414

8–11 years

416

12+ years

516

About this medicine

Type: medicine.

Questions owners ask

Can Omeprazole cause didn't work as expected in horses?: 1,708 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 32 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Pergolide 143 reports · 12% of its reports
Didn't work as expected after Ceftiofur 64 reports · 5.3% of its reports
Didn't work as expected after Detomidine 306 reports · 31% of its reports
Didn't work as expected after Flunixin Meglumine 46 reports · 7.4% of its reports
Didn't work as expected after Ketamine 463 reports · 82% of its reports
Didn't work as expected after Polysulfated Glycosaminoglycan 40 reports · 7.8% of its reports
Didn't work as expected after Xylazine 268 reports · 58% of its reports
Didn't work as expected after Sucralfate 384 reports · 98% of its reports
Didn't work as expected after Butorphanol 84 reports · 28% of its reports
Didn't work as expected after Ponazuril 48 reports · 27% of its reports

All reported side effects of Omeprazole in horses · Medicines most reported with didn't work as expected