Didn't work as expected after Ponazuril in horses

The FDA has received 48 reports of didn't work as expected in horses after Ponazuril. That is 27% of all reports for this medicine, compared with 23% across reports for all horse medicines.

48Reports

21%Marked serious

4.2%Recovered

4.2%Died or euthanised

32 daysTypical onset

How soon it started

Same day

3 12%

1–2 days

1 3.8%

3–7 days

0 0.0%

1–4 weeks

7 27%

Over a month

15 58%

How the animals did

Recovered

2 4.2%

Still unwell when reported

7 15%

Died

1 2.1%

Euthanised

1 2.1%

Not known

37 77%

Problems reported at the same time

Wobbliness (ataxia)

4 8.3%

Behaviour change

2 4.2%

Neurological signs

2 4.2%

Central nervous system disorder

1 2.1%

Swelling

1 2.1%

Lethargy

1 2.1%

Weight loss

1 2.1%

Eye pain

1 2.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ponazuril cause didn't work as expected in horses?: 48 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 32 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Omeprazole 1,708 reports · 88% of its reports
Didn't work as expected after Pergolide 143 reports · 12% of its reports
Didn't work as expected after Ceftiofur 64 reports · 5.3% of its reports
Didn't work as expected after Detomidine 306 reports · 31% of its reports
Didn't work as expected after Flunixin Meglumine 46 reports · 7.4% of its reports
Didn't work as expected after Ketamine 463 reports · 82% of its reports
Didn't work as expected after Polysulfated Glycosaminoglycan 40 reports · 7.8% of its reports
Didn't work as expected after Xylazine 268 reports · 58% of its reports
Didn't work as expected after Sucralfate 384 reports · 98% of its reports
Didn't work as expected after Butorphanol 84 reports · 28% of its reports

All reported side effects of Ponazuril in horses · Medicines most reported with didn't work as expected