Didn't work as expected after Detomidine in horses

The FDA has received 306 reports of didn't work as expected in horses after Detomidine. That is 31% of all reports for this medicine, compared with 23% across reports for all horse medicines.

306Reports

29%Marked serious

46%Recovered

2.9%Died or euthanised

Same dayTypical onset

How soon it started

Same day

133 83%

1–2 days

10 6.3%

3–7 days

4 2.5%

1–4 weeks

8 5.0%

Over a month

5 3.1%

How the animals did

Recovered

142 46%

Still unwell when reported

4 1.3%

Died

5 1.6%

Euthanised

4 1.3%

Not known

151 49%

Problems reported at the same time

Underdose

34 11%

Potency, low

11 3.6%

Death

6 2.0%

Behaviour change

6 2.0%

Restlessness or agitation

5 1.6%

Sedation prolonged

5 1.6%

Medication error

5 1.6%

Swelling

4 1.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Detomidine cause didn't work as expected in horses?: 306 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Omeprazole 1,708 reports · 88% of its reports
Didn't work as expected after Pergolide 143 reports · 12% of its reports
Didn't work as expected after Ceftiofur 64 reports · 5.3% of its reports
Didn't work as expected after Flunixin Meglumine 46 reports · 7.4% of its reports
Didn't work as expected after Ketamine 463 reports · 82% of its reports
Didn't work as expected after Polysulfated Glycosaminoglycan 40 reports · 7.8% of its reports
Didn't work as expected after Xylazine 268 reports · 58% of its reports
Didn't work as expected after Sucralfate 384 reports · 98% of its reports
Didn't work as expected after Butorphanol 84 reports · 28% of its reports
Didn't work as expected after Ponazuril 48 reports · 27% of its reports

All reported side effects of Detomidine in horses · Medicines most reported with didn't work as expected