Gastric ulceration after Omeprazole in horses

45 reports to the FDA describe gastric ulceration in horses given Omeprazole. That is 2.3% of all reports for this medicine, compared with 0.3% across reports for all horse medicines, so it is reported unusually often with this medicine.

45Reports

98%Marked serious

16%Recovered

0.0%Died or euthanised

39 daysTypical onset

How soon it started

Same day

0 0.0%

1–2 days

0 0.0%

3–7 days

0 0.0%

1–4 weeks

2 15%

Over a month

11 85%

How the animals did

Recovered

6 13%

Recovered with lasting effects

1 2.2%

Still unwell when reported

5 11%

Not known

33 73%

Problems reported at the same time

Didn't work as expected

43 96%

Overdose

15 33%

Loss of appetite

3 6.7%

Uncoded sign

3 6.7%

Colic

3 6.7%

Pyloric ulcer

3 6.7%

Underdose

3 6.7%

Pain

2 4.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Omeprazole cause gastric ulceration in horses?: 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 39 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Omeprazole in horses · Medicines most reported with gastric ulceration