Gastric ulcer after Omeprazole in horses

The FDA has received 97 reports of gastric ulcer in horses after Omeprazole. That is 5.0% of all reports for this medicine, compared with 0.8% across reports for all horse medicines, so it is reported unusually often with this medicine.

97Reports

93%Marked serious

19%Recovered

2.1%Died or euthanised

31 daysTypical onset

How soon it started

Same day

3 7.0%

1–2 days

1 2.3%

3–7 days

1 2.3%

1–4 weeks

14 33%

Over a month

24 56%

How the animals did

Recovered

18 19%

Still unwell when reported

17 18%

Euthanised

2 2.1%

Not known

60 62%

Problems reported at the same time

Didn't work as expected

93 96%

Overdose

22 23%

Digestive tract disorder

9 9.3%

Colic

9 9.3%

Abdominal pain

5 5.2%

Loss of appetite

4 4.1%

Pyloric ulcer

4 4.1%

Underdose

3 3.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Omeprazole cause gastric ulcer in horses?: 97 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 31 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Omeprazole in horses · Medicines most reported with gastric ulcer