Blood problems after Ursodiol in dogs

The FDA has received 40 reports of blood problems in dogs after Ursodiol. That is 5.5% of all reports for this medicine, compared with 1.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports
88%Marked serious
7.5%Recovered
60%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
5 14%
1–2 days
3 8.6%
3–7 days
4 11%
1–4 weeks
10 29%
Over a month
13 37%

How the animals did

Recovered
2 5.0%
Recovered with lasting effects
1 2.5%
Still unwell when reported
12 30%
Died
5 13%
Euthanised
19 48%
Not known
1 2.5%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
4
8–11 years
20
12+ years
16

About this medicine

Type: medicine.

Questions owners ask

Can Ursodiol cause blood problems in dogs?
40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

All reported side effects of Ursodiol in dogs · Medicines most reported with blood problems