Diarrhea after Ursodiol in dogs

The FDA has received 131 reports of diarrhea in dogs after Ursodiol. That is 18% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

131Reports
65%Marked serious
22%Recovered
18%Died or euthanised
26 daysTypical onset
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How soon it started

Same day
13 13%
1–2 days
9 8.7%
3–7 days
7 6.7%
1–4 weeks
26 25%
Over a month
49 47%

How the animals did

Recovered
28 21%
Recovered with lasting effects
1 0.8%
Still unwell when reported
44 34%
Died
5 3.8%
Euthanised
19 15%
Not known
34 26%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
9
8–11 years
50
12+ years
67

About this medicine

Type: medicine.

Questions owners ask

Can Ursodiol cause diarrhea in dogs?
131 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 26 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

All reported side effects of Ursodiol in dogs · Medicines most reported with diarrhea