Proteinuria after Trazodone in dogs

The FDA has received 42 reports of proteinuria in dogs after Trazodone. That is 1.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

42Reports

64%Marked serious

9.5%Recovered

12%Died or euthanised

50 daysTypical onset

How soon it started

Same day

3 8.8%

1–2 days

0 0.0%

3–7 days

5 15%

1–4 weeks

6 18%

Over a month

20 59%

How the animals did

Recovered

4 9.5%

Still unwell when reported

19 45%

Died

2 4.8%

Euthanised

3 7.1%

Not known

14 33%

Problems reported at the same time

23 55%

18 43%

14 33%

13 31%

11 26%

11 26%

Abnormal ultrasound finding

10 24%

Decreased urine concentration

10 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause proteinuria in dogs?: 42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 50 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proteinuria with similar medicines

Proteinuria after Gabapentin 201 reports · 2.2% of its reports
Proteinuria after Selegiline (Anipryl) 21 reports · 0.5% of its reports
Proteinuria after Fluoxetine 23 reports · 0.9% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with proteinuria