Proteinuria after Gabapentin in dogs

The FDA has received 201 reports of proteinuria in dogs after Gabapentin. That is 2.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

201Reports

71%Marked serious

5.0%Recovered

22%Died or euthanised

23 daysTypical onset

How soon it started

Same day

16 10%

1–2 days

22 14%

3–7 days

16 10%

1–4 weeks

32 21%

Over a month

67 44%

How the animals did

Recovered

9 4.5%

Recovered with lasting effects

1 0.5%

Still unwell when reported

105 52%

Died

7 3.5%

Euthanised

38 19%

Not known

41 20%

Problems reported at the same time

101 50%

101 50%

72 36%

59 29%

52 26%

45 22%

44 22%

41 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause proteinuria in dogs?: 201 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 23 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proteinuria with similar medicines

Proteinuria after Selegiline (Anipryl) 21 reports · 0.5% of its reports
Proteinuria after Fluoxetine 23 reports · 0.9% of its reports
Proteinuria after Trazodone 42 reports · 1.7% of its reports

All reported side effects of Gabapentin in dogs · Medicines most reported with proteinuria