Lameness after Trazodone in dogs

58 reports to the FDA describe lameness in dogs given Trazodone. That is 2.3% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

58Reports

53%Marked serious

17%Recovered

14%Died or euthanised

27 daysTypical onset

How soon it started

Same day

8 19%

1–2 days

2 4.8%

3–7 days

5 12%

1–4 weeks

8 19%

Over a month

19 45%

How the animals did

Recovered

10 17%

Still unwell when reported

28 48%

Died

3 5.2%

Euthanised

5 8.6%

Not known

12 21%

Problems reported at the same time

Swelling

22 38%

Injection site reaction

14 24%

Breathing problems

11 19%

Loss of appetite

11 19%

Didn't work as expected

10 17%

Abnormal radiograph finding

9 16%

Liver problems

9 16%

Lethargy

9 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause lameness in dogs?: 58 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 27 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lameness with similar medicines

Lameness after Gabapentin 459 reports · 5.1% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with lameness