Lethargy after Tobramycin in dogs

The FDA has received 32 reports of lethargy in dogs after Tobramycin. That is 27% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

32Reports
78%Marked serious
16%Recovered
25%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
8 35%
1–2 days
6 26%
3–7 days
0 0.0%
1–4 weeks
6 26%
Over a month
3 13%

How the animals did

Recovered
2 6.3%
Recovered with lasting effects
3 9.4%
Still unwell when reported
11 34%
Died
1 3.1%
Euthanised
7 22%
Not known
8 25%

Problems reported at the same time

Neutrophilia
11 34%
Vomiting
10 31%
Liver problems
10 31%
Leucocytosis
9 28%
Death
8 25%
Swelling
8 25%

Age of the animals

Under 1 year
4
1–3 years
3
4–7 years
9
8–11 years
9
12+ years
7

About this medicine

Type: medicine.

Questions owners ask

Can Tobramycin cause lethargy in dogs?
32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Tobramycin in dogs · Medicines most reported with lethargy