Behaviour change after Sulfadimethoxine in dogs

The FDA has received 26 reports of behaviour change in dogs after Sulfadimethoxine. That is 2.8% of all reports for this medicine, compared with 2.5% across reports for all dog medicines.

26Reports
31%Marked serious
12%Recovered
31%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
7 50%
1–2 days
0 0.0%
3–7 days
4 29%
1–4 weeks
0 0.0%
Over a month
3 21%

How the animals did

Recovered
3 12%
Still unwell when reported
3 12%
Died
8 31%
Not known
12 46%

Problems reported at the same time

7 27%
Restlessness or agitation
4 15%

Age of the animals

Under 1 year
16
1–3 years
5
4–7 years
2
8–11 years
0
12+ years
2

About this medicine

Type: medicine.

Questions owners ask

Can Sulfadimethoxine cause behaviour change in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Sulfadimethoxine in dogs · Medicines most reported with behaviour change