Skin disorders after Spinosad (Comfortis) in dogs

124 reports to the FDA describe skin disorders in dogs given Spinosad. That is 0.2% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported less often than average with this medicine.

124Reports
27%Marked serious
36%Recovered
7.3%Died or euthanised
24 daysTypical onset
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How soon it started

Same day
26 30%
1–2 days
11 13%
3–7 days
1 1.1%
1–4 weeks
13 15%
Over a month
37 42%

How the animals did

Recovered
21 17%
Recovered with lasting effects
24 19%
Still unwell when reported
28 23%
Died
3 2.4%
Euthanised
6 4.8%
Not known
42 34%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
26
4–7 years
40
8–11 years
36
12+ years
4

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause skin disorders in dogs?
124 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 24 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin disorders with similar medicines

All reported side effects of Spinosad in dogs · Medicines most reported with skin disorders