Digestive tract disorder after Spinosad (Comfortis) in dogs

141 reports to the FDA describe digestive tract disorder in dogs given Spinosad. That is 0.2% of all reports for this medicine, compared with 2.0% across reports for all dog medicines, so it is reported less often than average with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause digestive tract disorder in dogs?

141 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 5 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Digestive tract disorder with similar medicines

• Digestive tract disorder after Lufenuron + Milbemycin Oxime (Sentinel) 108 reports · 0.4% of its reports
• Digestive tract disorder after Imidacloprid + Moxidectin (Advantage Multi) 46 reports · 0.4% of its reports
• Digestive tract disorder after Nitenpyram (Capstar) 30 reports · 0.3% of its reports
• Digestive tract disorder after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 33 reports · 0.3% of its reports
• Digestive tract disorder after Fipronil + S-methoprene (Frontline Plus) 27 reports · 0.9% of its reports

All reported side effects of Spinosad in dogs · Medicines most reported with digestive tract disorder