Cough after Spinosad (Comfortis) in dogs

299 reports to the FDA describe cough in dogs given Spinosad. That is 0.5% of all reports for this medicine, compared with 0.8% across reports for all dog medicines, so it is reported less often than average with this medicine.

299Reports
28%Marked serious
30%Recovered
14%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
57 38%
1–2 days
24 16%
3–7 days
6 4.0%
1–4 weeks
14 9.3%
Over a month
50 33%

How the animals did

Recovered
52 17%
Recovered with lasting effects
37 12%
Still unwell when reported
35 12%
Died
32 11%
Euthanised
10 3.3%
Not known
133 44%

Problems reported at the same time

Age of the animals

Under 1 year
23
1–3 years
68
4–7 years
72
8–11 years
80
12+ years
48

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause cough in dogs?
299 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cough with similar medicines

All reported side effects of Spinosad in dogs · Medicines most reported with cough