Urinary tract disorder after Selamectin (Revolution) in dogs

The FDA has received 34 reports of urinary tract disorder in dogs after Selamectin. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines.

34Reports
2.9%Marked serious
0.0%Recovered
15%Died or euthanised
–Typical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How the animals did

Still unwell when reported
1 2.9%
Died
5 15%
Not known
28 82%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
10
4–7 years
8
8–11 years
8
12+ years
2

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause urinary tract disorder in dogs?
34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary tract disorder with similar medicines

All reported side effects of Selamectin in dogs · Medicines most reported with urinary tract disorder