Haemorrhage after Selamectin (Revolution) in dogs

29 reports to the FDA describe haemorrhage in dogs given Selamectin. That is 0.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines.

29Reports
24%Marked serious
6.9%Recovered
38%Died or euthanised
6 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
3 25%
1–2 days
2 17%
3–7 days
2 17%
1–4 weeks
2 17%
Over a month
3 25%

How the animals did

Recovered
1 3.4%
Recovered with lasting effects
1 3.4%
Still unwell when reported
3 10%
Died
9 31%
Euthanised
2 6.9%
Not known
13 45%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
8
4–7 years
7
8–11 years
6
12+ years
3

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause haemorrhage in dogs?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Haemorrhage with similar medicines

All reported side effects of Selamectin in dogs · Medicines most reported with haemorrhage