Arthritis after Sarolaner (Simparica) in dogs
The FDA has received 20 reports of arthritis in dogs after Sarolaner. That is 0.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.
20Reports
60%Marked serious
5.0%Recovered
15%Died or euthanised
–Typical onset
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How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Sarolaner kills fleas, ticks and some mites; monthly.
Products with this ingredient include Simparica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.
Questions owners ask
- Can Sarolaner cause arthritis in dogs?
- 20 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Arthritis with similar medicines
- Arthritis after Fluralaner (Bravecto) 123 reports · 0.2% of its reports
- Arthritis after Afoxolaner (NexGard) 55 reports · 0.1% of its reports
- Arthritis after Lotilaner (Credelio) 30 reports · 0.3% of its reports
All reported side effects of Sarolaner in dogs · Medicines most reported with arthritis