Arthritis after Fluralaner (Bravecto) in dogs

123 reports to the FDA describe arthritis in dogs given Fluralaner. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

123Reports
87%Marked serious
21%Recovered
17%Died or euthanised
16 daysTypical onset
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How soon it started

Same day
4 11%
1–2 days
6 17%
3–7 days
5 14%
1–4 weeks
5 14%
Over a month
16 44%

How the animals did

Recovered
6 4.9%
Recovered with lasting effects
20 16%
Still unwell when reported
61 50%
Died
7 5.7%
Euthanised
14 11%
Not known
15 12%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
18
8–11 years
54
12+ years
45

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause arthritis in dogs?
123 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Arthritis with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with arthritis