Loss of appetite after Pyriproxyfen in dogs

The FDA has received 28 reports of loss of appetite in dogs after Pyriproxyfen. That is 9.4% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

28Reports
43%Marked serious
39%Recovered
21%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
4 20%
1–2 days
4 20%
3–7 days
2 10%
1–4 weeks
4 20%
Over a month
6 30%

How the animals did

Recovered
10 36%
Recovered with lasting effects
1 3.6%
Still unwell when reported
9 32%
Died
1 3.6%
Euthanised
5 18%
Not known
2 7.1%

Problems reported at the same time

15 54%
11 39%
Blood problems
7 25%
Liver problems
7 25%
Weight loss
6 21%
Death
6 21%
Neutrophilia
5 18%
Tremors
4 14%

Age of the animals

Under 1 year
4
1–3 years
9
4–7 years
4
8–11 years
8
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Pyriproxyfen cause loss of appetite in dogs?
28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Pyriproxyfen in dogs · Medicines most reported with loss of appetite