Swelling after Pyrantel in dogs

337 reports to the FDA describe swelling in dogs given Pyrantel. That is 7.0% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

337Reports

33%Marked serious

38%Recovered

10%Died or euthanised

Same dayTypical onset

How soon it started

Same day

216 81%

1–2 days

21 7.8%

3–7 days

7 2.6%

1–4 weeks

9 3.4%

Over a month

15 5.6%

How the animals did

Recovered

127 38%

Recovered with lasting effects

1 0.3%

Still unwell when reported

113 34%

Died

27 8.0%

Euthanised

8 2.4%

Not known

61 18%

Problems reported at the same time

168 50%

113 34%

62 18%

45 13%

35 10%

34 10%

32 9.5%

27 8.0%

Age of the animals

Under 1 year

155

1–3 years

106

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause swelling in dogs?: 337 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Pyrantel + Sarolaner (Simparica Trio) 400 reports · 0.7% of its reports
Swelling after Febantel + Praziquantel + Pyrantel (Drontal Plus) 87 reports · 1.3% of its reports
Swelling after Fenbendazole 129 reports · 2.2% of its reports
Swelling after Praziquantel + Pyrantel 44 reports · 1.2% of its reports
Swelling after Praziquantel 88 reports · 7.9% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with swelling