Swelling after Praziquantel in dogs

88 reports to the FDA describe swelling in dogs given Praziquantel. That is 7.9% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

88Reports

40%Marked serious

24%Recovered

1.1%Died or euthanised

1 daysTypical onset

How soon it started

Same day

18 42%

1–2 days

6 14%

3–7 days

9 21%

1–4 weeks

10 23%

Over a month

0 0.0%

How the animals did

Recovered

21 24%

Still unwell when reported

9 10%

Died

1 1.1%

Not known

57 65%

Problems reported at the same time

Injection site reaction

32 36%

Lethargy

9 10%

Itching

8 9.1%

Vomiting

6 6.8%

Allergic reaction

6 6.8%

Skin redness

5 5.7%

Hair loss

4 4.5%

Loss of appetite

4 4.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms.

Questions owners ask

Can Praziquantel cause swelling in dogs?: 88 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Pyrantel + Sarolaner (Simparica Trio) 400 reports · 0.7% of its reports
Swelling after Febantel + Praziquantel + Pyrantel (Drontal Plus) 87 reports · 1.3% of its reports
Swelling after Fenbendazole 129 reports · 2.2% of its reports
Swelling after Pyrantel 337 reports · 7.0% of its reports
Swelling after Praziquantel + Pyrantel 44 reports · 1.2% of its reports

All reported side effects of Praziquantel in dogs · Medicines most reported with swelling