Injection site reaction after Praziquantel in dogs

124 reports to the FDA describe injection site reaction in dogs given Praziquantel. That is 11% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

124Reports

45%Marked serious

24%Recovered

0.8%Died or euthanised

7 daysTypical onset

How soon it started

Same day

13 18%

1–2 days

15 21%

3–7 days

11 15%

1–4 weeks

29 40%

Over a month

4 5.6%

How the animals did

Recovered

30 24%

Still unwell when reported

7 5.6%

Died

1 0.8%

Not known

86 69%

Problems reported at the same time

Swelling

32 26%

Hair loss

10 8.1%

Vocalising

8 6.5%

Skin redness

8 6.5%

Lethargy

6 4.8%

Itching

4 3.2%

Application site reaction

4 3.2%

Didn't stop worms

4 3.2%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms.

Questions owners ask

Can Praziquantel cause injection site reaction in dogs?: 124 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Pyrantel + Sarolaner (Simparica Trio) 28 reports · 0.1% of its reports
Injection site reaction after Fenbendazole 20 reports · 0.3% of its reports
Injection site reaction after Pyrantel 47 reports · 1.0% of its reports

All reported side effects of Praziquantel in dogs · Medicines most reported with injection site reaction