Injection site reaction after Pyrantel in dogs

The FDA has received 47 reports of injection site reaction in dogs after Pyrantel. That is 1.0% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

47Reports

17%Marked serious

17%Recovered

4.3%Died or euthanised

1 daysTypical onset

How soon it started

Same day

13 39%

1–2 days

7 21%

3–7 days

2 6.1%

1–4 weeks

7 21%

Over a month

4 12%

How the animals did

Recovered

8 17%

Still unwell when reported

21 45%

Euthanised

2 4.3%

Not known

16 34%

Problems reported at the same time

11 23%

11 23%

7 15%

7 15%

4 8.5%

3 6.4%

Abnormal radiograph finding

3 6.4%

Wobbliness (ataxia)

3 6.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause injection site reaction in dogs?: 47 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Pyrantel + Sarolaner (Simparica Trio) 28 reports · 0.1% of its reports
Injection site reaction after Fenbendazole 20 reports · 0.3% of its reports
Injection site reaction after Praziquantel 124 reports · 11% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with injection site reaction