Allergic reaction after Pyrantel in dogs

The FDA has received 351 reports of allergic reaction in dogs after Pyrantel. That is 7.3% of all reports for this medicine, compared with 2.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

351Reports

48%Marked serious

40%Recovered

6.8%Died or euthanised

Same dayTypical onset

How soon it started

Same day

261 89%

1–2 days

19 6.5%

3–7 days

1 0.3%

1–4 weeks

6 2.1%

Over a month

5 1.7%

How the animals did

Recovered

141 40%

Still unwell when reported

128 36%

Died

21 6.0%

Euthanised

3 0.9%

Not known

58 17%

Problems reported at the same time

184 52%

168 48%

68 19%

61 17%

53 15%

49 14%

47 13%

41 12%

Age of the animals

Under 1 year

117

1–3 years

151

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause allergic reaction in dogs?: 351 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Allergic reaction with similar medicines

Allergic reaction after Pyrantel + Sarolaner (Simparica Trio) 569 reports · 1.1% of its reports
Allergic reaction after Febantel + Praziquantel + Pyrantel (Drontal Plus) 58 reports · 0.9% of its reports
Allergic reaction after Fenbendazole 95 reports · 1.6% of its reports
Allergic reaction after Praziquantel + Pyrantel 55 reports · 1.5% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with allergic reaction