Kidney problems after Pyrantel in dogs

The FDA has received 81 reports of kidney problems in dogs after Pyrantel. That is 1.7% of all reports for this medicine, compared with 2.4% across reports for all dog medicines.

81Reports

65%Marked serious

6.2%Recovered

51%Died or euthanised

5 daysTypical onset

How soon it started

Same day

10 18%

1–2 days

12 22%

3–7 days

10 18%

1–4 weeks

11 20%

Over a month

12 22%

How the animals did

Recovered

4 4.9%

Recovered with lasting effects

1 1.2%

Still unwell when reported

20 25%

Died

19 23%

Euthanised

22 27%

Not known

15 19%

Problems reported at the same time

45 56%

45 56%

44 54%

41 51%

29 36%

27 33%

26 32%

21 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause kidney problems in dogs?: 81 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Pyrantel + Sarolaner (Simparica Trio) 293 reports · 0.5% of its reports
Kidney problems after Febantel + Praziquantel + Pyrantel (Drontal Plus) 55 reports · 0.8% of its reports
Kidney problems after Fenbendazole 76 reports · 1.3% of its reports
Kidney problems after Praziquantel + Pyrantel 22 reports · 0.6% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with kidney problems