Hyperphosphataemia after Pyrantel in dogs

33 reports to the FDA describe hyperphosphataemia in dogs given Pyrantel. That is 0.7% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

33Reports

67%Marked serious

15%Recovered

45%Died or euthanised

2 daysTypical onset

How soon it started

Same day

7 26%

1–2 days

7 26%

3–7 days

4 15%

1–4 weeks

5 19%

Over a month

4 15%

How the animals did

Recovered

5 15%

Still unwell when reported

8 24%

Died

5 15%

Euthanised

10 30%

Not known

5 15%

Problems reported at the same time

22 67%

21 64%

21 64%

19 58%

15 45%

15 45%

11 33%

10 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause hyperphosphataemia in dogs?: 33 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

Hyperphosphataemia after Pyrantel + Sarolaner (Simparica Trio) 62 reports · 0.1% of its reports
Hyperphosphataemia after Febantel + Praziquantel + Pyrantel (Drontal Plus) 26 reports · 0.4% of its reports
Hyperphosphataemia after Fenbendazole 33 reports · 0.6% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with hyperphosphataemia