Foaming at the mouth after Pyrantel in dogs

The FDA has received 22 reports of foaming at the mouth in dogs after Pyrantel. That is 0.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

22Reports

73%Marked serious

9.1%Recovered

27%Died or euthanised

Same dayTypical onset

How soon it started

Same day

10 63%

1–2 days

4 25%

3–7 days

0 0.0%

1–4 weeks

2 13%

Over a month

0 0.0%

How the animals did

Recovered

2 9.1%

Still unwell when reported

9 41%

Died

5 23%

Euthanised

1 4.5%

Not known

5 23%

Problems reported at the same time

10 45%

10 45%

8 36%

8 36%

6 27%

6 27%

5 23%

5 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause foaming at the mouth in dogs?: 22 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Foaming at the mouth with similar medicines

Foaming at the mouth after Pyrantel + Sarolaner (Simparica Trio) 147 reports · 0.3% of its reports
Foaming at the mouth after Praziquantel + Pyrantel 25 reports · 0.7% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with foaming at the mouth