Disorientation after Pyrantel in dogs

The FDA has received 33 reports of disorientation in dogs after Pyrantel. That is 0.7% of all reports for this medicine, compared with 1.0% across reports for all dog medicines.

33Reports

58%Marked serious

18%Recovered

24%Died or euthanised

3 daysTypical onset

How soon it started

Same day

5 25%

1–2 days

5 25%

3–7 days

5 25%

1–4 weeks

3 15%

Over a month

2 10%

How the animals did

Recovered

5 15%

Recovered with lasting effects

1 3.0%

Still unwell when reported

7 21%

Died

3 9.1%

Euthanised

5 15%

Not known

12 36%

Problems reported at the same time

10 30%

10 30%

9 27%

8 24%

8 24%

7 21%

7 21%

7 21%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause disorientation in dogs?: 33 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Disorientation with similar medicines

Disorientation after Pyrantel + Sarolaner (Simparica Trio) 493 reports · 0.9% of its reports
Disorientation after Febantel + Praziquantel + Pyrantel (Drontal Plus) 34 reports · 0.5% of its reports
Disorientation after Fenbendazole 46 reports · 0.8% of its reports
Disorientation after Praziquantel + Pyrantel 33 reports · 0.9% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with disorientation