Adipsia after Pyrantel in dogs

The FDA has received 82 reports of adipsia in dogs after Pyrantel. That is 1.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

82Reports

27%Marked serious

9.8%Recovered

34%Died or euthanised

1 daysTypical onset

How soon it started

Same day

14 45%

1–2 days

11 35%

3–7 days

0 0.0%

1–4 weeks

5 16%

Over a month

1 3.2%

How the animals did

Recovered

6 7.3%

Recovered with lasting effects

2 2.4%

Still unwell when reported

6 7.3%

Died

24 29%

Euthanised

4 4.9%

Not known

40 49%

Problems reported at the same time

75 91%

39 48%

37 45%

26 32%

24 29%

7 8.5%

7 8.5%

7 8.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Pyrantel cause adipsia in dogs?: 82 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Adipsia with similar medicines

Adipsia after Pyrantel + Sarolaner (Simparica Trio) 99 reports · 0.2% of its reports
Adipsia after Febantel + Praziquantel + Pyrantel (Drontal Plus) 53 reports · 0.8% of its reports
Adipsia after Fenbendazole 102 reports · 1.7% of its reports
Adipsia after Praziquantel + Pyrantel 26 reports · 0.7% of its reports

All reported side effects of Pyrantel in dogs · Medicines most reported with adipsia