Intestinal perforation after Propofol in dogs

27 reports to the FDA describe intestinal perforation in dogs given Propofol. That is 0.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports
96%Marked serious
11%Recovered
85%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
2 11%
1–2 days
2 11%
3–7 days
6 32%
1–4 weeks
7 37%
Over a month
2 11%

How the animals did

Recovered
3 11%
Died
8 30%
Euthanised
15 56%
Not known
1 3.7%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
14
4–7 years
7
8–11 years
6
12+ years
0

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause intestinal perforation in dogs?
27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Intestinal perforation with similar medicines

All reported side effects of Propofol in dogs · Medicines most reported with intestinal perforation