Corneal ulcer after Ofloxacin in dogs

The FDA has received 50 reports of corneal ulcer in dogs after Ofloxacin. That is 45% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

50Reports
90%Marked serious
24%Recovered
10%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
22 54%
1–2 days
7 17%
3–7 days
1 2.4%
1–4 weeks
5 12%
Over a month
6 15%

How the animals did

Recovered
9 18%
Recovered with lasting effects
3 6.0%
Still unwell when reported
16 32%
Died
1 2.0%
Euthanised
4 8.0%
Not known
17 34%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
13
4–7 years
10
8–11 years
13
12+ years
13

About this medicine

Type: medicine.

Questions owners ask

Can Ofloxacin cause corneal ulcer in dogs?
50 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Corneal ulcer with similar medicines

All reported side effects of Ofloxacin in dogs · Medicines most reported with corneal ulcer