Corneal ulcer after Atropine in dogs

The FDA has received 27 reports of corneal ulcer in dogs after Atropine. That is 3.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports
100%Marked serious
19%Recovered
15%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
12 60%
1–2 days
5 25%
3–7 days
1 5.0%
1–4 weeks
1 5.0%
Over a month
1 5.0%

How the animals did

Recovered
5 19%
Still unwell when reported
3 11%
Euthanised
4 15%
Not known
15 56%

Problems reported at the same time

Keratoconjunctivitis sicca
12 44%
11 41%
Squinting
11 41%
10 37%
Blepharospasm
10 37%

Age of the animals

Under 1 year
2
1–3 years
9
4–7 years
6
8–11 years
4
12+ years
5

About this medicine

Type: medicine.

Questions owners ask

Can Atropine cause corneal ulcer in dogs?
27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Corneal ulcer with similar medicines

All reported side effects of Atropine in dogs · Medicines most reported with corneal ulcer