Skin lump after Oclacitinib (Apoquel) in dogs

334 reports to the FDA describe skin lump in dogs given Oclacitinib. That is 1.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

334Reports

46%Marked serious

8.7%Recovered

7.8%Died or euthanised

61 daysTypical onset

How soon it started

Same day

21 9.3%

1–2 days

9 4.0%

3–7 days

20 8.8%

1–4 weeks

30 13%

Over a month

147 65%

How the animals did

Recovered

29 8.7%

Still unwell when reported

241 72%

Died

9 2.7%

Euthanised

17 5.1%

Not known

38 11%

Problems reported at the same time

Abnormal cytology

64 19%

Didn't work as expected

41 12%

35 10%

28 8.4%

25 7.5%

24 7.2%

23 6.9%

22 6.6%

Age of the animals

Under 1 year

1–3 years

4–7 years

122

8–11 years

120

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause skin lump in dogs?: 334 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 61 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin lump with similar medicines

Skin lump after Cyclosporine (Atopica) 119 reports · 0.8% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with skin lump