Dermal mass after Oclacitinib (Apoquel) in dogs

The FDA has received 601 reports of dermal mass in dogs after Oclacitinib. That is 2.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

601Reports
53%Marked serious
13%Recovered
6.8%Died or euthanised
70 daysTypical onset
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How soon it started

Same day
34 8.5%
1–2 days
7 1.8%
3–7 days
17 4.3%
1–4 weeks
66 17%
Over a month
274 69%

How the animals did

Recovered
76 13%
Recovered with lasting effects
2 0.3%
Still unwell when reported
437 73%
Died
15 2.5%
Euthanised
26 4.3%
Not known
45 7.5%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
83
4–7 years
206
8–11 years
214
12+ years
74

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause dermal mass in dogs?
601 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 70 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dermal mass with similar medicines

All reported side effects of Oclacitinib in dogs · Medicines most reported with dermal mass