Injection site reaction after Oclacitinib (Apoquel) in dogs

105 reports to the FDA describe injection site reaction in dogs given Oclacitinib. That is 0.4% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported less often than average with this medicine.

105Reports

41%Marked serious

14%Recovered

2.9%Died or euthanised

27 daysTypical onset

How soon it started

Same day

8 11%

1–2 days

8 11%

3–7 days

6 8.2%

1–4 weeks

16 22%

Over a month

35 48%

How the animals did

Recovered

15 14%

Still unwell when reported

63 60%

Died

2 1.9%

Euthanised

1 1.0%

Not known

24 23%

Problems reported at the same time

Swelling

34 32%

Didn't work as expected

33 31%

19 18%

16 15%

16 15%

15 14%

12 11%

11 10%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause injection site reaction in dogs?: 105 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 27 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Cyclosporine (Atopica) 21 reports · 0.1% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with injection site reaction