Head tilt - ear disorder after Oclacitinib (Apoquel) in dogs

53 reports to the FDA describe head tilt - ear disorder in dogs given Oclacitinib. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

53Reports

38%Marked serious

11%Recovered

7.5%Died or euthanised

11 daysTypical onset

How soon it started

Same day

9 23%

1–2 days

5 13%

3–7 days

4 10%

1–4 weeks

8 21%

Over a month

13 33%

How the animals did

Recovered

4 7.5%

Recovered with lasting effects

2 3.8%

Still unwell when reported

32 60%

Euthanised

4 7.5%

Not known

11 21%

Problems reported at the same time

20 38%

11 21%

10 19%

8 15%

8 15%

7 13%

5 9.4%

Horizontal nystagmus

5 9.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause head tilt - ear disorder in dogs?: 53 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Head tilt - ear disorder with similar medicines

Head tilt - ear disorder after Cyclosporine (Atopica) 53 reports · 0.3% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with head tilt - ear disorder