Ear discharge after Oclacitinib (Apoquel) in dogs

68 reports to the FDA describe ear discharge in dogs given Oclacitinib. That is 0.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

68Reports

65%Marked serious

19%Recovered

8.8%Died or euthanised

20 daysTypical onset

How soon it started

Same day

4 9.3%

1–2 days

1 2.3%

3–7 days

3 7.0%

1–4 weeks

19 44%

Over a month

16 37%

How the animals did

Recovered

10 15%

Recovered with lasting effects

3 4.4%

Still unwell when reported

24 35%

Died

6 8.8%

Not known

25 37%

Problems reported at the same time

Didn't work as expected

32 47%

20 29%

14 21%

11 16%

11 16%

Head shake - ear disorder

10 15%

Skin rash or irritation

9 13%

Ear canal inflammation

9 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Oclacitinib controls itching from allergies (tablet, a JAK inhibitor).

Products with this ingredient include Apoquel. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Oclacitinib cause ear discharge in dogs?: 68 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 20 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Ear discharge with similar medicines

Ear discharge after Cyclosporine (Atopica) 23 reports · 0.2% of its reports

All reported side effects of Oclacitinib in dogs · Medicines most reported with ear discharge