Lethargy after Mycophenolate in dogs

The FDA has received 27 reports of lethargy in dogs after Mycophenolate. That is 39% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports
100%Marked serious
3.7%Recovered
74%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
4 17%
1–2 days
3 13%
3–7 days
1 4.2%
1–4 weeks
8 33%
Over a month
8 33%

How the animals did

Recovered with lasting effects
1 3.7%
Still unwell when reported
4 15%
Died
7 26%
Euthanised
13 48%
Not known
2 7.4%

Problems reported at the same time

18 67%
Leucocytosis
11 41%
Vomiting
10 37%
Diarrhea
10 37%
Breathing problems
9 33%

Age of the animals

Under 1 year
1
1–3 years
2
4–7 years
15
8–11 years
5
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Mycophenolate cause lethargy in dogs?
27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Mycophenolate in dogs · Medicines most reported with lethargy